SCHEMBL281976

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2306814	0.85	KMT2A (0.40)	KMT2AMEN1SCN9ASMN1; SMN2TP53
	SCHEMBL2304533	0.85	PDE7A (0.39)	KMT2AMEN1SCN9ASMN1; SMN2RAB9A
	SCHEMBL1612096	0.80	KMT2A (0.63)	KMT2AMEN1SMN1; SMN2ALDH1A1MTOR
	SCHEMBL24281158	0.75	KMT2A (0.44)	KMT2AMEN1PDE7AAKR1B1
	SCHEMBL281810	0.74	SCN9A (0.43)	SCN9ANPC1SMN1; SMN2RAB9ATP53
	SCHEMBL384666	0.74	KMT2A (0.43)	KMT2AMEN1SCN9ASMN1; SMN2TP53
	SCHEMBL281811	0.73	KMT2A (0.42)	KMT2AMEN1SMN1; SMN2ALDH1A1MTOR
	SCHEMBL1611952	0.72	KMT2A (0.63)	KMT2AMEN1SCN9AALDH1A1MTOR
	SCHEMBL11734265	0.70	POLB (0.46)	KMT2AMEN1SCN9APDE7AAKR1B1
	SCHEMBL2303883	0.68	PDE7A (0.37)	KMT2ASCN9ASMN1; SMN2RAB9APDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.