Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614552 | 0.92 | LMNA (0.70) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL1614553 | 0.92 | LMNA (0.70) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL2489079 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL4070152 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL4070148 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL30746 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL8872231 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL59457 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL8872489 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 | |
| SCHEMBL4421069 | 0.91 | LMNA (0.68) | LMNASMN1; SMN2TDP1APPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104460037-B | The method and apparatus of Ophthalmoligic instrument including cycloid aligned liquid-crystal layer | 庄臣及庄臣视力保护公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108535885-A | Method and apparatus for electroactive iris ring eyeglass | 庄臣及庄臣视力保护公司 | 2018-09-14 | — | — | CN | disclosed |
| CN-107783313-A | Variable optical Ophthalmoligic instrument including liquid crystal cell | 庄臣及庄臣视力保护公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-107561730-A | For the method for the variable optical Ophthalmoligic instrument for forming the liquid crystal cell for including shaping | 庄臣及庄臣视力保护公司 | 2018-01-09 | — | — | CN | disclosed |