Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.48 |
| ▸ | ESR1 | P03372 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058893 | 0.81 | CSNK2A2 (0.58) | ESR2ESR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27935833 | 0.78 | ADORA3 (0.56) | MEN1KMT2AGAAMAOBMAOA | |
| SCHEMBL6933533 | 0.76 | ESR2 (0.55) | MEN1KMT2AATMPABPC1ERAP1 | |
| SCHEMBL9135495 | 0.74 | CSNK2A2 (0.69) | ESR2ESR1KDM4EALDH1A1GAA | |
| SCHEMBL106506 | 0.71 | HSD17B3 (0.58) | MEN1KMT2AERAP1ESR2KDM4E | |
| SCHEMBL28642209 | 0.71 | MAOB (0.47) | MEN1KMT2AALDH1A1MAOBMAPK1 | |
| SCHEMBL16702494 | 0.71 | MEN1 (0.52) | MEN1KMT2AATMPABPC1ERAP1 | |
| SCHEMBL4178185 | 0.71 | MCL1 (0.66) | MEN1KMT2AATMPABPC1ERAP1 | |
| SCHEMBL28417210 | 0.70 | CYP3A4 (0.47) | MEN1KMT2AATMPABPC1ERAP1 | |
| SCHEMBL3130742 | 0.70 | KDM4E (0.55) | MEN1KMT2AATMPABPC1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674055-A | Hydroxycoumarin derivatives of 4 trifluoromethyl 7 and its preparation method and application | 南京农业大学 | 2018-02-09 | — | — | CN | disclosed |