Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264835 | 0.78 | ADORA3 (0.51) | ADORA3ADORA2AADORA1MAOBMAOA | |
| SCHEMBL27950166 | 0.78 | GPR55 (0.45) | ADORA3ADORA2AADORA1ELANEMEN1 | |
| SCHEMBL28197879 | 0.78 | MEN1 (0.50) | MAOBMAOAGAAMEN1KMT2A | |
| SCHEMBL28160921 | 0.76 | ADORA3 (0.59) | ADORA3ADORA2AADORA1MAOBMAOA | |
| SCHEMBL383681 | 0.74 | HPGD (0.55) | MAOBMAOAPOLBGAANPC1 | |
| SCHEMBL7544470 | 0.74 | HPGD (0.55) | MAOBMAOAPOLBGAANPC1 | |
| SCHEMBL13534184 | 0.73 | ADORA3 (0.56) | ADORA3ADORA2AADORA1MAOBMAOA | |
| SCHEMBL13534175 | 0.73 | ADORA3 (0.56) | ADORA3ADORA2AADORA1MAOBMAOA | |
| SCHEMBL830863 | 0.73 | ADORA3 (0.56) | ADORA3ADORA2AADORA1MAOBMAOA | |
| Ammonia Solution, Strong SCHEMBL6994460 | 0.72 | HPGD (0.53) | MAOBMAOAPOLBGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554074-B | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2015-03-25 | — | — | CN | disclosed |
| CN-103554074-A | Preparation method of 3-trifluoromethyl coumarin derivative | UNIV SOOCHOW | 2014-02-05 | — | — | CN | disclosed |