Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28197879 | 0.81 | MEN1 (0.50) | ESR1ESR2KDM4EALDH1A1HPGD | |
| SCHEMBL3265344 | 0.74 | ERN1 (0.49) | CSNK2A2CSNK2BCSNK2A1ESR1ESR2 | |
| SCHEMBL27986597 | 0.74 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ESR1ESR2 | |
| SCHEMBL106506 | 0.71 | HSD17B3 (0.58) | ESR2MCL1HSD17B3MAPTKDM4E | |
| SCHEMBL12040002 | 0.71 | CA12 (0.53) | ARHSD17B3MAPTLMNAKDM4E | |
| SCHEMBL27935833 | 0.71 | ADORA3 (0.56) | ADORA2AADORA1ADORA3POLB | |
| SCHEMBL15842332 | 0.66 | PGR (0.43) | ARHSD17B3KDM4EALDH1A1HPGD | |
| SCHEMBL15842386 | 0.65 | HTT (0.39) | MCL1ARHSD17B3MAPTKDM4E | |
| SCHEMBL7544470 | 0.65 | HPGD (0.55) | ESR1ESR2MAPTTP53LMNA | |
| SCHEMBL6828285 | 0.65 | ESR2 (0.68) | CSNK2A2CSNK2BCSNK2A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529972-B | Kinases inhibitor cumarin and preparation method thereof and medical applications | Langzhao Technology (Beijing) Co.,Ltd. (CN) | 2016-05-18 | — | — | CN | disclosed |