Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28197508 | 0.86 | HSD17B10 (0.46) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL20971490 | 0.81 | BTK (0.35) | — | |
| SCHEMBL20971433 | 0.75 | NCF1 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL20971517 | 0.74 | L3MBTL1 (0.36) | HRH3 | |
| SCHEMBL20971324 | 0.73 | RORC (0.39) | — | |
| SCHEMBL19923091 | 0.72 | KDM4E (0.36) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21872262 | 0.68 | BACE1 (0.32) | — | |
| SCHEMBL18390571 | 0.67 | MEN1 (0.49) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18390576 | 0.67 | PDCD1LG2 (0.46) | POLBMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20971484 | 0.67 | NCF1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349896-A | Heterocyclic compounds as FGFR inhibitors | 南京天印健华医药科技有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107619388-A | Heterocyclic compound as FGFR inhibitor | 南京天印健华医药科技有限公司 | 2018-01-23 | — | — | CN | disclosed |