Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.52 |
| ▸ | CTSS | P25774 | 13/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86185 | 0.84 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL86153 | 0.84 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL4118840 | 0.84 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL18055375 | 0.78 | CA1 (0.63) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL21085559 | 0.78 | CA1 (0.63) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL16228758 | 0.77 | CA2 (0.45) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL1370051 | 0.76 | CTSK (0.55) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL5496903 | 0.76 | CTSK (0.59) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL19021911 | 0.76 | CA1 (0.58) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL902049 | 0.76 | CA1 (0.58) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143212-B | Tripeptide epoxy ketone protease inhibitors | 欧尼斯治疗公司 | 2018-02-23 | — | — | CN | disclosed |