Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857658 | 1.00 | CTSS (0.57) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL28198598 | 1.00 | CTSS (0.57) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL22404737 | 0.93 | CTSS (0.64) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL3355326 | 0.93 | CTSS (0.64) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL85543 | 0.93 | CTSS (0.64) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL18941938 | 0.91 | CTSS (0.57) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL21883788 | 0.89 | MMP1 (0.53) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL11828072 | 0.89 | CTSL (0.56) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL7409389 | 0.88 | CTSS (0.65) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL1486267 | 0.88 | CTSS (0.63) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143212-B | Tripeptide epoxy ketone protease inhibitors | 欧尼斯治疗公司 | 2018-02-23 | — | — | CN | disclosed |