SCHEMBL28198650

SCHEMBL28198650

CC(C)(C)c1ncccn1.[Cu]

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.33
HSP90AA1 P07900 1/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30
CCR1 P32246 1/20 0.30
CCR5 P51681 1/20 0.30
CCR8 P51685 1/20 0.30
METAP1 P53582 1/20 0.30
BLM P54132 1/20 0.30
HIF1A Q16665 1/20 0.30
DOHH Q9BU89 1/20 0.30
P4HTM Q9NXG6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179267 0.97 HDAC8 (0.35) HDAC8HSP90AA1KDM4EALDH1A1KMT2A
SCHEMBL31175998 0.94 HDAC8 (0.33) HDAC8HSP90AA1KDM4EALDH1A1KMT2A
Hydrochloric Acid SCHEMBL6587339 0.94 KDM4E (0.36) HDAC8HSP90AA1KDM4EALDH1A1KMT2A
SCHEMBL31194454 0.94 HDAC8 (0.33) HDAC8HSP90AA1KDM4EALDH1A1KMT2A
SCHEMBL28130826 0.78
SCHEMBL28130822 0.75
SCHEMBL19814728 0.73 HSP90AA1 (0.38) HDAC8HSP90AA1
SCHEMBL31692011 0.73 HDAC8 (0.32) HDAC8HSP90AA1
SCHEMBL22047644 0.73 HDAC8 (0.32) HDAC8HSP90AA1
SCHEMBL85656 0.73 HDAC8 (0.32) HDAC8HSP90AA1KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478628-B Application of tert-butyl pyrimidine copper (I) triazole dinuclear complex in stimulus response luminescent color-changing material 江西理工大学 2024-10-18 CN claimed
CN-114478628-B Application of tert-butyl pyrimidine copper (I) triazole dinuclear complex in stimulus response luminescent color-changing material 江西理工大学 2024-10-18 CN disclosed
CN-114478628-B Application of tert-butyl pyrimidine copper (I) triazole dinuclear complex in stimulus response luminescent color-changing material 江西理工大学 2024-10-18 CN disclosed
CN-114478628-A Application of tert-butyl pyrimidine triazole copper [ I ] dinuclear complex in stimulus response luminescent and photochromic material 江西理工大学 2022-05-13 CN disclosed
CN-106432290-B T-butyl pyrimidines triazole copper [I] binuclear complex luminescent material and preparation method 江西理工大学 2018-01-19 CN disclosed