Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221377 | 0.82 | HDAC8 (0.32) | HDAC8HSP90AA1 | |
| SCHEMBL1491767 | 0.75 | MALT1 (0.38) | HDAC8HSP90AA1 | |
| SCHEMBL179267 | 0.75 | HDAC8 (0.35) | HDAC8HSP90AA1 | |
| Hydrochloric Acid SCHEMBL6587339 | 0.73 | KDM4E (0.36) | HDAC8HSP90AA1 | |
| SCHEMBL28128144 | 0.73 | MALT1 (0.36) | HDAC8HSP90AA1 | |
| Hydrochloric Acid SCHEMBL6192480 | 0.73 | MALT1 (0.36) | HDAC8HSP90AA1 | |
| SCHEMBL28198650 | 0.73 | HDAC8 (0.33) | HDAC8HSP90AA1 | |
| SCHEMBL31175998 | 0.73 | HDAC8 (0.33) | HDAC8HSP90AA1 | |
| SCHEMBL31194454 | 0.73 | HDAC8 (0.33) | HDAC8HSP90AA1 | |
| SCHEMBL20909664 | 0.71 | MAP4K1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | HDAC8 1049/4885HSP90AA1 2429/4885MDM2 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.