SCHEMBL28199374

SCHEMBL28199374

CC1(C(N)=O)C=CC=CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8521845 0.82
SCHEMBL7535171 0.82
SCHEMBL1767501 0.80 CYP3A4 (0.31)
SCHEMBL1044296 0.80 CYP3A4 (0.34)
SCHEMBL6897212 0.78
SCHEMBL31259143 0.78
SCHEMBL28206514 0.78 DGAT1 (0.31)
SCHEMBL5347884 0.77 MEN1 (0.33)
SCHEMBL4229895 0.75 MAPK1 (0.38)
Carbamic Acid SCHEMBL25424778 0.74 ACHE (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768480-A Treatment with Protein Kinase C (PKC) inhibitors and cytotoxic agents 剑桥企业有限公司 2023-03-07 CN disclosed
CN-105189453-B Sulfamoyl aryl amide and its purposes as the medicine for treating hepatitis B 爱尔兰詹森科学公司 2018-04-10 CN disclosed
CN-105102453-B benzimidazolone derivatives as bromodomain inhibitors 吉利德科学公司 2018-04-06 CN disclosed