Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL28199547

Clc1ccccc1.OC(=S)c1ccccc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NPC1 O15118 3/20 0.43
ALDH1A1 P00352 3/20 0.43
RAB9A P51151 2/20 0.43
EPHX1 P07099 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
NOX1 Q9Y5S8 1/20 0.42
CYP1A2 P05177 1/20 0.42
MAPT P10636 2/20 0.41
MAOB P27338 1/20 0.39
PTGS2 P35354 1/20 0.39
HSP90AA1 P07900 1/20 0.39
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
TRPV6 Q9H1D0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL28579899 0.86 CES2 (0.54) TSHRCES2CES1MEN1KMT2A
Thiobenzoic Acid SCHEMBL37018 0.86
Thiobenzoic Acid SCHEMBL160729 0.86 ALDH1A1 (0.50) TSHRCES2CES1MEN1KMT2A
Thiobenzoic Acid SCHEMBL15282156 0.86 ALDH1A1 (0.50) TSHRCES2CES1MEN1KMT2A
Thiobenzoic Acid SCHEMBL28199536 0.86 ALDH1A1 (0.50) TSHRCES2CES1MEN1KMT2A
SCHEMBL11367245 0.83 TSHR (0.55) TSHRCES2CES1NPC1ALDH1A1
Thiobenzoic Acid SCHEMBL11305253 0.83 ALDH1A1 (0.48) TSHRCES2CES1MEN1KMT2A
Thiobenzoic Acid SCHEMBL284149 0.83 ALDH1A1 (0.48) TSHRCES2CES1MEN1KMT2A
Thiobenzoic Acid SCHEMBL21806751 0.83 ALDH1A1 (0.48) TSHRCES2CES1MEN1KMT2A
Thiobenzoic Acid SCHEMBL20741485 0.83 MAPT (0.48) TSHRCES2CES1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107722049-B Preparation and application of novel ionic binuclear Schiff base titanium complex 山西医科大学 2020-06-30 CN disclosed
CN-107722049-A A kind of preparation and its application of novel ionic double-core schiff bases titanium complex 山西医科大学 2018-02-23 CN disclosed