SCHEMBL28199569

SCHEMBL28199569

NNC(=O)N(N)c1cc[nH]c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.33
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28796226 0.79 ALDH1A1 (0.39) CAPN1ALDH1A1KMT2A
SCHEMBL6206534 0.72 NPSR1 (0.48) ALDH1A1KMT2A
SCHEMBL28180042 0.71 CYP3A4 (0.47) ALDH1A1KMT2A
SCHEMBL28116855 0.69 ALDH1A1 (0.48) ALDH1A1KMT2A
SCHEMBL21767229 0.69 OGG1 (0.48) KMT2A
SCHEMBL9037566 0.69 ALDH1A1 (0.39) ALDH1A1KMT2A
SCHEMBL28177790 0.69 KDM4E (0.44) ALDH1A1
SCHEMBL22251766 0.69 KDM4E (0.48) ALDH1A1KMT2A
SCHEMBL27842747 0.68 TSHR (0.46) ALDH1A1KMT2A
SCHEMBL22251861 0.67 IDO1 (0.43) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104220072-B Methods for treating stroke-related sensorimotor impairment using aminopyridines 阿索尔达治疗公司 2018-04-17 CN disclosed
CN-107708699-A Tumor biomarkers and its application 源生公司 2018-02-16 CN disclosed