SCHEMBL6206534

SCHEMBL6206534

NNC(=O)N(N)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.48
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 2/20 0.41
CTSD P07339 1/20 0.41
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.37
GLA P06280 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27467210 0.92 ALDH1A1 (0.45) NPSR1ALDH1A1KMT2ARAB9ACTSD
SCHEMBL27892920 0.88 NPC1 (0.40) NPSR1ALDH1A1KMT2ARAB9ACTSD
SCHEMBL27558619 0.85 RAB9A (0.53) ALDH1A1KMT2ARAB9ANPC1L3MBTL1
SCHEMBL6889531 0.84 NPSR1 (0.56) NPSR1ALDH1A1KMT2ARAB9ACTSD
SCHEMBL9036196 0.83 CA1 (0.52) NPSR1ALDH1A1KMT2ANPC1POLB
Hydrochloric Acid SCHEMBL9004700 0.83 NPSR1 (0.54) NPSR1ALDH1A1KMT2ARAB9ACTSD
SCHEMBL27842747 0.82 TSHR (0.46) ALDH1A1KMT2ANPC1POLBMEN1
SCHEMBL28180042 0.81 CYP3A4 (0.47) ALDH1A1KMT2ARAB9ANPC1HTT
SCHEMBL11726572 0.81 NPSR1 (0.46) NPSR1ALDH1A1KMT2ARAB9ANPC1
SCHEMBL27770539 0.80 KDM4E (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1177967-C Enzymatic method for textile dyeing ŵ����÷�����޹�˾ 2004-12-01 CN claimed
CN-1216914-A Enzyme for dyeing keratinous fibres NOVO NORDISK AS (DK) 1999-05-19 CN claimed
WO-2020150210-A1 TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) 2020-07-23 WO disclosed
CN-107548301-A Contain composition of the menthol as soothing agent 西姆莱斯股份公司 2018-01-05 CN disclosed
CN-105164107-B Radiosensitizer compounds for use in conjunction with radiation 卢庆彬 2017-12-05 CN disclosed
CN-103998531-B Three aromatic azo methine direct dyess, dye composite, implementation and the purposes for including at least one such dyestuff 欧莱雅 2017-07-28 CN disclosed
CN-104320972-B Herbicidal composition comprising uracil compound as active ingredient 东部福阿母韩农株式会社 2017-05-24 CN disclosed
CN-106661326-A Resin precursor, resin composition containing the same, polyimide resin film, and method for producing the same 旭化成株式会社 2017-05-10 CN disclosed
CN-103517703-B Stain and application thereof 天野酶制品株式会社 2016-11-09 CN disclosed
CN-105980442-A Curing agent for epoxy resins 赫克塞尔合成有限公司 2016-09-28 CN disclosed
CN-103619846-B 1-aryl-4-methyl-[1,2,4] triazole [4,3-a] quinoxaline derivant 詹森药业有限公司 2016-08-17 CN disclosed
CN-1205754-A Enzymatic method for dyeing NOVO NORDISK BIOCHEM INC (US) 1999-01-20 CN disclosed
CN-1204957-A Composition for the oxidation dyeing of keratin fibres, comprising a nonionic amphiphilic polymer OREAL (FR) 1999-01-13 CN disclosed
CN-1186655-A Oxidation dye composition for keratin fibres, comprising anionic amphiphilic polymer OREAL (FR) 1998-07-08 CN disclosed
CN-1181926-A Oxidation dye composition for keratin fibres, comprising anionic amphiphilic polymer OREAL (FR) 1998-05-20 CN disclosed
US-5571843-A Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof INNOTHERA (FR) 1996-11-05 US disclosed
EP-0566445-A1 Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy INNOTHERA (FR) 1993-10-20 EP disclosed
EP-0012983-B1 DIAMINOPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF AMINOBENZIMIDAZOLONES-(2) HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-31 EP disclosed
US-4246196-A CHEMICAL INTERMEDIATES IN THE PRODUCTION OF AMINOBENZIMIDAZOLONES HOECHST AG. (DE) 1981-01-20 US disclosed
EP-0012983-A1 Diaminophenyl ureas, process for their preparation and their use in the preparation of aminobenzimidazolones-(2) HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed