Cyanate

Cyanate

SCHEMBL28199844

Cc1ccc(OP(O)(O)=S)cc1.N#CO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.45
TSHR P16473 2/20 0.45
LMNA P02545 2/20 0.39
ACHE P22303 1/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP2A6 P11509 1/20 0.35
PTK2B Q14289 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 2/20 0.33
AR P10275 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6691437 0.90 TSHR (0.54) CYP3A4TSHRLMNAACHEALDH1A1
SCHEMBL28286382 0.88 TSHR (0.52) CYP3A4TSHRLMNAACHEALDH1A1
SCHEMBL27798162 0.83 TSHR (0.48) CYP3A4TSHRLMNAACHEALDH1A1
Cyanate SCHEMBL10695476 0.80 SRC (0.48) TSHRKDM4ECYP2C9CYP2C19
Carbamic Acid SCHEMBL27866020 0.78 CYP3A4 (0.47) CYP3A4TSHRLMNAALDH1A1PTK2B
SCHEMBL1974047 0.77 TSHR (0.54) CYP3A4TSHRLMNAACHEALDH1A1
SCHEMBL27549937 0.77 TSHR (0.41) CYP3A4TSHRLMNAACHEALDH1A1
SCHEMBL2354339 0.76 CA2 (0.43) LMNAALDH1A1CYP2A6KDM4EGAA
SCHEMBL28462057 0.74 CYP3A4 (0.47) CYP3A4TSHRLMNAACHEALDH1A1
SCHEMBL869948 0.74 TSHR (0.50) CYP3A4TSHRLMNAACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109585920-A Lithium ion battery and its electrolyte 欣旺达电子股份有限公司 2019-04-05 CN claimed
CN-108863851-A A kind of branching type water-based carbodiimides type crosslinking agent and preparation method thereof 成都创世芯研科技有限公司 2018-11-23 CN disclosed
CN-104932155-B Sealant for liquid crystal dripping process, upper and lower conductive material and liquid crystal display cells 积水化学工业株式会社 2018-04-03 CN disclosed