Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19508022 | 0.86 | CA12 (0.39) | LMNAMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL18007685 | 0.82 | LMNA (0.49) | LMNAMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL23329033 | 0.76 | MEN1 (0.32) | LMNAMEN1KMT2AKDM4EGRN | |
| SCHEMBL18007631 | 0.76 | KDM4E (0.31) | KDM4EGRNSORT1 | |
| SCHEMBL18029742 | 0.70 | BAZ2B (0.40) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19508023 | 0.70 | ALDH1A1 (0.40) | KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL22680981 | 0.68 | RAB9A (0.50) | LMNAMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL20885970 | 0.67 | RECQL (0.33) | KMT2A | |
| SCHEMBL22012923 | 0.67 | MAPT (0.35) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22019982 | 0.67 | GAA (0.35) | MEN1KMT2AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735400-A | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-02-23 | — | — | CN | disclosed |