SCHEMBL163434

SCHEMBL163434

Fc1ccccc1N(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
NFE2L2 Q16236 4/20 0.38
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
TAAR1 Q96RJ0 3/20 0.33
ESR1 P03372 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP2C19 P33261 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
AOC3 Q16853 1/20 0.31
IDO1 P14902 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29523028 1.00 ACHE (0.39) ACHENFE2L2CES2CES1TAAR1
SCHEMBL29132912 0.97 ACHE (0.38) ACHENFE2L2CES2CES1TAAR1
Methane SCHEMBL7871211 0.97 ACHE (0.38) ACHENFE2L2CES2CES1TAAR1
Methyl Alcohol SCHEMBL27472875 0.92 ACHE (0.40) ACHENFE2L2CES2CES1TAAR1
SCHEMBL437240 0.81 APOBEC3G (0.33) ALDH1A1SMN1; SMN2
SCHEMBL8375069 0.78 ACHE (0.36) ACHENFE2L2CES2CES1TAAR1
SCHEMBL998479 0.78 ACHE (0.36) ACHENFE2L2CES2CES1TAAR1
SCHEMBL2455081 0.78 CES2 (0.39) ACHECES2CES1SLC6A2SLC6A4
SCHEMBL17508132 0.78 ACHE (0.42) ACHENFE2L2CES2CES1TAAR1
SCHEMBL5730844 0.78 ACHE (0.36) ACHENFE2L2CES2CES1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119674089-A Composite current collector and preparation method and application thereof 江苏正力新能电池技术股份有限公司 2025-03-21 CN claimed
CN-119432288-A Adhesive composition and preparation method and application thereof 江苏正力新能电池技术股份有限公司 2025-02-14 CN claimed
CN-117352833-A Organic-inorganic composite polymer solid electrolyte and preparation method and application thereof 中国科学院大学 2024-01-05 CN claimed
US-11814335-B1 Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms PTC Innovations, LLC (US) 2023-11-14 US claimed
CN-115916221-A Anticancer activity of perborate 阿利亚制药公司 2023-04-04 CN claimed
WO-2022228449-A1 PREPARATION METHOD FOR POLYIMIDE RESIN AND THIN FILM THEREOF 上海瑞暨新材料科技有限公司 2022-11-03 WO claimed
CN-114891198-A Preparation method of poly (fluorophenyl ester) polymer with low dielectric loss 西安交通大学 2022-08-12 CN claimed
CN-112581856-B Temperature indicating label 苏州和萃新材料有限公司 2022-07-19 CN claimed
CN-113201136-B Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2022-01-07 CN claimed
CN-113789086-A High-temperature color-changing ink and label 江苏集萃智能液晶科技有限公司 2021-12-14 CN claimed
CN-113201136-A Preparation method of polyimide resin and film thereof 上海瑞暨新材料科技有限公司 2021-08-03 CN claimed
CN-112581856-A Temperature indicating label 苏州和萃新材料有限公司 2021-03-30 CN claimed
EP-1461313-A1 HUMAN ADAM-10 INHIBITORS Exelixis, Inc. (US) 2004-09-29 EP claimed
WO-2003051825-A1 HUMAN ADAM-10 INHIBITORS EXELIXIS, INC. (US) 2003-06-26 WO claimed
EP-0682673-A4 POROMERIC MATERIAL HAVING UNIFORMLY DISTRIBUTED ELECTRETS. BUDINGER WILLIAM D (US) 1996-02-21 EP claimed
EP-0682673-A1 POROMERIC MATERIAL HAVING UNIFORMLY DISTRIBUTED ELECTRETS Budinger, William D (US) 1995-11-22 EP claimed
WO-1994018242-A1 POROMERIC MATERIAL HAVING UNIFORMLY DISTRIBUTED ELECTRETS BUDINGER WILLIAM D (US) 1994-08-18 WO claimed
US-12582604-B2 Stable solid dispersion of a B-RAF kinase dimer inhibitor, methods of preparation, and uses therefor BEIGENE, LTD. (KY) 2026-03-24 US disclosed
US-3993647-A ANTIMYCOTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed
US-3950354-A ANTIMYCOTIC AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12582604-B2 Stable solid dispersion of a B-RAF kinase dimer inhibitor, methods of preparation, and uses therefor BRAF, RAF1, ARAF ACHE 4376/4885NFE2L2 3202/4885CES2 4528/4885
US-11814335-B1 Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms F8, F5, OPRM1 ACHE 4/4885NFE2L2 1038/4885CES2 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.