Phosphoric Acid

Phosphoric Acid

SCHEMBL28200101

BrNNc1cc(Br)ccc1Br.O=P(O)(O)O

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.41
TLR9 Q9NR96 1/20 0.41
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 2/20 0.38
ALOX15 P16050 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
BTK Q06187 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PLK3 Q9H4B4 1/20 0.38
MMP2 P08253 3/20 0.34
CA12 O43570 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28200158 0.86 HSP90AA1 (0.43) HSP90AA1TLR9MEN1ALDH1A1KMT2A
Phosphoric Acid SCHEMBL28200730 0.85 NPC1 (0.40) HSP90AA1TLR9MEN1ALDH1A1KMT2A
Oxalic Acid SCHEMBL28200792 0.85 ALDH1A1 (0.44) HSP90AA1TLR9MEN1ALDH1A1KMT2A
Sulfuric Acid SCHEMBL28200108 0.85 HSP90AA1 (0.41) HSP90AA1TLR9MEN1ALDH1A1KMT2A
SCHEMBL20985016 0.81 HSP90AA1 (0.41) HSP90AA1TLR9MEN1ALDH1A1KMT2A
Phosphoric Acid SCHEMBL20985015 0.79 ALDH1A1 (0.39) HSP90AA1TLR9MEN1ALDH1A1KMT2A
Phosphoric Acid SCHEMBL28200154 0.78 CYP3A4 (0.32) CYP3A4TSHR
Phosphoric Acid SCHEMBL28200695 0.77 HTT (0.42) MEN1KMT2AGAALMNANPSR1
SCHEMBL20984668 0.73 GAA (0.50) HSP90AA1TLR9MEN1ALDH1A1KMT2A
Phosphoric Acid SCHEMBL28856291 0.72 MMP2 (0.52) MEN1ALDH1A1KMT2AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed