Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | IDO1 | P14902 | 4/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TGM1 | P22735 | 1/20 | 0.42 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460051 | 0.86 | CYP2A6 (0.47) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL28200187 | 0.84 | IDO1 (0.45) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| Phosphoric Acid SCHEMBL28856291 | 0.83 | MMP2 (0.52) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| Sulfuric Acid SCHEMBL28200085 | 0.83 | IDO1 (0.52) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| Oxalic Acid SCHEMBL28200760 | 0.78 | ACP1 (0.39) | GAAMAOAMAOBALDH1A1MAPT | |
| Oxalic Acid SCHEMBL28200725 | 0.78 | MAPT (0.40) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| Oxalic Acid SCHEMBL28200756 | 0.76 | GAA (0.49) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| Oxalic Acid SCHEMBL20984619 | 0.76 | MAOA (0.50) | SMN1; SMN2GAAMAOAMAOBMAPT | |
| SCHEMBL9461879 | 0.73 | GAA (0.62) | SMN1; SMN2GAAMAOAMAOBALDH1A1 | |
| SCHEMBL20984621 | 0.73 | GAA (0.62) | SMN1; SMN2GAAMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |