Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200762 | 0.86 | ACP1 (0.33) | ACP1 | |
| Hydrochloric Acid SCHEMBL28200855 | 0.84 | IDO1 (0.36) | ACP1 | |
| Phosphoric Acid SCHEMBL28856228 | 0.83 | MMP2 (0.38) | ACP1 | |
| Sulfuric Acid SCHEMBL28200853 | 0.83 | ACP1 (0.47) | ACP1 | |
| Oxalic Acid SCHEMBL28200798 | 0.81 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| Oxalic Acid SCHEMBL28200756 | 0.80 | GAA (0.49) | MEN1KMT2AALDH1A1MAPTMAOA | |
| Oxalic Acid SCHEMBL28200201 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1MAPTGFER | |
| Oxalic Acid SCHEMBL28200725 | 0.74 | MAPT (0.40) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL8794958 | 0.72 | ACP1 (0.37) | ACP1ALDH1A1 | |
| Oxalic Acid SCHEMBL28200133 | 0.72 | GPR35 (0.41) | GPR35AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |