Mb07344

Mb07344

SCHEMBL282003

Cc1cc(OCP(=O)(O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 20/20 1.00
THRA P10827 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mb07344 SCHEMBL29378732 1.00 THRB (1.00) THRBTHRA
SCHEMBL13946957 0.92 THRB (0.85) THRBTHRA
SCHEMBL3160842 0.92 THRB (0.85) THRBTHRA
SCHEMBL282073 0.91 THRB (1.00) THRBTHRA
SCHEMBL13703175 0.91 THRB (0.83) THRBTHRA
SCHEMBL3157077 0.90 THRB (0.81) THRBTHRA
SCHEMBL28770829 0.90 THRB (0.81) THRBTHRA
SCHEMBL23791465 0.89 THRB (0.81) THRBTHRA
SCHEMBL282795 0.89 THRB (1.00) THRBTHRA
SCHEMBL13044659 0.88 THRB (0.83) THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260053761-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER UNIV OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2026-02-26 US claimed
EP-4677084-A1 MODIFIED SHORT INERFERING NUCLEIC ACID (SINA) MOLECULES AND USES THEREOF Aligos Therapeutics, Inc. (US) 2026-01-14 EP claimed
US-20250304916-A1 METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS TRAILHEAD BIOSYSTEMS INC (US) 2025-10-02 US claimed
US-20250243491-A1 PNPLA3-TARGETING SHORT INTERFERING RNA (SIRNA) MOLECULES AND USES THEREOF ALIGOS THERAPEUTICS, INC. (US) 2025-07-31 US claimed
EP-4561704-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2025-06-04 EP claimed
US-20250115872-A1 GENERATION OF BROWN ADIPOCYTES FROM HUMAN PLURIPOTENT STEM CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2025-04-10 US claimed
EP-4473093-A1 GENERATION OF BROWN ADIPOCYTES FROM HUMAN PLURIPOTENT STEM CELLS The Brigham and Women's Hospital, Inc. (US) 2024-12-11 EP claimed
CN-118871570-A Production of brown adipocytes from human pluripotent stem cells 布里格姆妇女医院 2024-10-29 CN claimed
WO-2024187038-A1 MODIFIED SHORT INERFERING NUCLEIC ACID (SINA) MOLECULES AND USES THEREOF ALIGOS THERAPEUTICS, INC. (US) 2024-09-12 WO claimed
WO-2024182446-A2 PNPLA3-TARGETING SHORT INTERFERING RNA (SIRNA) MOLECULES AND USES THEREOF ALIGOS THERAPEUTICS, INC. (US) 2024-09-06 WO claimed
US-20230255974-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE 2023-08-17 US claimed
WO-2023150555-A1 GENERATION OF BROWN ADIPOCYTES FROM HUMAN PLURIPOTENT STEM CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2023-08-10 WO claimed
CN-116286663-A In vitro production of human pluripotent stem cell-derived functional beta cells 詹森生物科技公司 2023-06-23 CN claimed
CN-115894554-A Preparation method of phosphonic acid compound 烟台药物研究所 2023-04-04 CN claimed
CN-109415693-B In vitro production of human pluripotent stem cell-derived functional beta cells 詹森生物科技公司 2023-03-21 CN claimed
WO-2023039076-A1 MODIFIED SHORT INTERFERING NUCLEIC ACID (SINA) MOLECULES AND USES THEREOF ALIGOS THERAPEUTICS, INC. (US) 2023-03-16 WO claimed
WO-2023034937-A1 PNPLA3-TARGETING SHORT INTERFERING RNA (SIRNA) MOLECULES AND USES THEREOF ALIGOS THERAPEUTICS, INC. (US) 2023-03-09 WO claimed
EP-2938723-B1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS INTO PANCREATIC ENDOCRINE CELLS USING HB9 REGULATORS JANSSEN BIOTECH INC (US) 2023-02-01 EP claimed
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP claimed
EP-3954759-A1 USE OF SMALL MOLECULES TO ENHANCE MAFA EXPRESSION IN PANCREATIC ENDOCRINE CELLS Janssen Biotech, Inc. (US) 2022-02-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053761-A1 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER THRA, THRB, TRHR THRB 2/4885THRA 1/4885
US-20250243491-A1 PNPLA3-TARGETING SHORT INTERFERING RNA (SIRNA) MOLECULES AND USES THEREOF PNPLA2, BCDIN3D, PNP THRB 2145/4885THRA 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.