Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161173 | 0.86 | ESR2 (0.53) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL8512875 | 0.86 | ESR1 (0.58) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL15064151 | 0.86 | ESR1 (0.58) | MAPTESR1ESR2LMNAHSD17B10 | |
| SCHEMBL26017755 | 0.84 | ESR2 (0.60) | MAPTESR1ESR2LMNAHSD17B10 | |
| SCHEMBL20776033 | 0.81 | ESR1 (0.53) | MAPTESR1ESR2LMNAHSD17B10 | |
| SCHEMBL19374106 | 0.80 | ESR1 (0.67) | MAPTESR1ESR2HSD17B10MAPK1 | |
| SCHEMBL14947867 | 0.80 | ESR2 (0.55) | MAPTESR1ESR2MAPK1HTT | |
| SCHEMBL16116627 | 0.80 | ESR1 (0.58) | MAPTESR1ESR2LMNATSHR | |
| SCHEMBL13784103 | 0.79 | ESR1 (0.51) | MAPTESR1ESR2LMNAMAPK1 | |
| SCHEMBL25752070 | 0.79 | ALDH1A1 (0.53) | MAPTESR1ESR2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540663-B | Soluble bipolar host material with high glass transition temperature, and preparation and application thereof | 华南理工大学 | 2020-04-28 | — | — | CN | claimed |
| CN-107540663-A | Soluble high glass-transition temperature bipolar host material and its preparation and application | 华南理工大学 | 2018-01-05 | — | — | CN | claimed |
| CN-107540663-B | Soluble bipolar host material with high glass transition temperature, and preparation and application thereof | 华南理工大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-107540663-B | Soluble bipolar host material with high glass transition temperature, and preparation and application thereof | 华南理工大学 | 2020-04-28 | — | — | CN | disclosed |
| CN-107540663-A | Soluble high glass-transition temperature bipolar host material and its preparation and application | 华南理工大学 | 2018-01-05 | — | — | CN | disclosed |