SCHEMBL14947867

SCHEMBL14947867

CC(C)(C)c1ccc(-n2c(-c3cc(-c4nc5ccccc5n4-c4ccc(C(C)(C)C)cc4)cc(-c4nc5ccccc5n4-c4ccc(C(C)(C)C)cc4)c3)nc3ccccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.55
ESR1 P03372 4/20 0.55
GRIA1 P42261 1/20 0.50
CACNG8 Q8WXS5 1/20 0.50
CACNG2 Q9Y698 1/20 0.50
MAPK1 P28482 2/20 0.47
HTT P42858 1/20 0.47
PTGS2 P35354 1/20 0.45
AKT1 P31749 1/20 0.44
AKT2 P31751 1/20 0.44
AKT3 Q9Y243 1/20 0.44
ADORA2A P29274 1/20 0.44
HDAC1 Q13547 3/20 0.43
HDAC8 Q9BY41 3/20 0.43
HDAC6 Q9UBN7 3/20 0.43
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RECQL P46063 1/20 0.42
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26017755 0.93 ESR2 (0.60) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL19374106 0.91 ESR1 (0.67) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL12453626 0.90 ESR2 (0.46) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL15783217 0.90 MAPK1 (0.54) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL18708547 0.89 AKT1 (0.61) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL15064151 0.88 ESR1 (0.58) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL14552149 0.86 ESR2 (0.50) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL28161173 0.86 ESR2 (0.53) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL24714168 0.86 PTGER4 (0.48) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL12114717 0.85 ESR1 (0.47) ESR2ESR1GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element UDC IRELAND LIMITED (IE) 2023-07-11 US disclosed
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element UDC IRELAND LIMITED (IE) 2023-07-11 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20130270530-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND COMPOUND UDC IRELAND LIMITED (IE) 2013-10-17 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130214259-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUNDS AND MATERIALS USED FOR THE ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-08-22 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 ESR2 278/4885ESR1 43/4885GRIA1 5/4885
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element ALDH1A2, AOC2, AOX1 ESR2 98/4885ESR1 13/4885GRIA1 953/4885
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element L1CAM, ZYX, H1-0 ESR2 55/4885ESR1 14/4885GRIA1 130/4885
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 ESR2 620/4885ESR1 274/4885GRIA1 198/4885
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element LAS1L, CCNL2, CDC5L ESR2 42/4885ESR1 5/4885GRIA1 497/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 ESR2 620/4885ESR1 274/4885GRIA1 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.