Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210907 | 0.89 | PARP1 (0.50) | KIF11PARP14MAPTMEN1KMT2A | |
| SCHEMBL28059318 | 0.86 | POLB (0.49) | KIF11CYP1A2TNKS2MAPTMEN1 | |
| SCHEMBL1180982 | 0.83 | KIF11 (0.59) | KIF11CYP1A2CYP2C19TNKS2ABCB1 | |
| SCHEMBL27673124 | 0.83 | APP (0.44) | PARP14PARP1CDK4CCND1POLB | |
| SCHEMBL27770093 | 0.83 | BCHE (0.50) | KIF11PARP14PARP1CDK4CCND1 | |
| SCHEMBL21647358 | 0.81 | CDK4 (0.52) | KIF11MAPTMEN1KMT2ACDK4 | |
| SCHEMBL29930364 | 0.81 | CDK4 (0.52) | KIF11MAPTMEN1KMT2ACDK4 | |
| SCHEMBL5810425 | 0.80 | KIF11 (0.75) | KIF11PARP14CYP1A2MAPTMEN1 | |
| SCHEMBL29119809 | 0.77 | KIF11 (0.70) | KIF11PARP14CYP1A2MAPTMEN1 | |
| SCHEMBL17999711 | 0.77 | KIF11 (0.55) | KIF11PARP14CYP1A2CYP2C19TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663169-A | A kind of 6H naphtho-s [2,1,8,7 klmn] acridine derivatives and its application | 北京鼎材科技有限公司 | 2018-02-06 | — | — | CN | disclosed |