Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200469 | 0.89 | KIF11 (0.53) | PARP1CDK4CCND1KIF11NPC1 | |
| SCHEMBL28127569 | 0.81 | CDK4 (0.58) | PARP1CDK4CCND1CDK5CDK5R1 | |
| SCHEMBL28532214 | 0.81 | CDK4 (0.39) | PARP1CDK4CCND1PLA2G7GSK3B | |
| SCHEMBL15939764 | 0.80 | PARP1 (0.46) | PARP1CDK4CCND1FGFR1FLT1 | |
| SCHEMBL28221114 | 0.79 | CDK4 (0.43) | PARP1CDK4CCND1FGFR1FLT1 | |
| SCHEMBL28059318 | 0.75 | POLB (0.49) | PARP1CDK4CCND1CDK5CDK5R1 | |
| SCHEMBL10094651 | 0.74 | PLA2G7 (0.71) | PLA2G7CDK5CDK5R1NPC1RAB9A | |
| SCHEMBL32690798 | 0.73 | PARP1 (0.48) | PARP1CDK4CCND1CDK5CDK5R1 | |
| SCHEMBL27770093 | 0.73 | BCHE (0.50) | PARP1CDK4CCND1CCNB2CDK1 | |
| SCHEMBL27673124 | 0.73 | APP (0.44) | PARP1CDK4CCND1CHEK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107880027-A | It is a kind of using triazine as the compound of core and its application on organic electroluminescence device | 江苏三月光电科技有限公司 | 2018-04-06 | — | — | CN | disclosed |