Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15939764 | 0.84 | PARP1 (0.46) | KIF11ABCB1ALDH1A1PARP1 | |
| SCHEMBL28200469 | 0.83 | KIF11 (0.53) | KIF11ABCB1MAPTMEN1KMT2A | |
| SCHEMBL20348696 | 0.81 | ABCB1 (0.75) | KIF11ABCB1MAPTMEN1KMT2A | |
| SCHEMBL3887451 | 0.81 | POLB (0.51) | KIF11MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL1181051 | 0.79 | KIF11 (0.55) | KIF11ABCB1MAPTMEN1KMT2A | |
| SCHEMBL27447266 | 0.79 | KIF11 (0.59) | KIF11ABCB1MAPTMEN1KMT2A | |
| SCHEMBL31188776 | 0.79 | KIF11 (0.59) | KIF11ABCB1MAPTMEN1KMT2A | |
| SCHEMBL3887813 | 0.79 | FTO (0.54) | KIF11MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6826973 | 0.79 | KIF11 (0.59) | KIF11ABCB1MAPTMEN1KMT2A | |
| SCHEMBL869230 | 0.78 | MAPT (0.54) | KIF11MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011342-A | The preparation based on carboline and carbazole for detecting neurological dysfunction | 伊莱利利公司 | 2017-08-04 | — | — | CN | disclosed |
| US-20110046378-A1 | Novel Imaging Agents for Detecting Neurological Dysfunction | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046378-A1 | Novel Imaging Agents for Detecting Neurological Dysfunction | FABP7, SLC18A3, TSPO | KIF11 2051/4885ABCB1 1276/4885MAPT 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.