Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.55 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.55 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269604 | 0.96 | ALDH1A1 (0.59) | SIRT2SIRT1SIRT3TRPV1ALDH1A1 | |
| SCHEMBL13779847 | 0.88 | TRPV1 (0.66) | TRPV1ALDH1A1RAB9ANPC1 | |
| SCHEMBL28197185 | 0.86 | PLAU (0.60) | TRPV1RAB9ANPC1LOXL2F2 | |
| SCHEMBL28956237 | 0.85 | KMT2A (0.57) | NR1H4HPSEITGB3ITGA2BLOXL2 | |
| SCHEMBL6681834 | 0.85 | KCNK3 (0.69) | SIRT1HPSERAB9ANPC1 | |
| SCHEMBL1229626 | 0.84 | MEN1 (0.71) | SIRT2SIRT1SIRT3HPSERAB9A | |
| SCHEMBL8462054 | 0.82 | NR1H4 (0.59) | ALDH1A1NR1H4HPSERAB9A | |
| SCHEMBL17683761 | 0.82 | ALDH1A1 (0.57) | SIRT2SIRT1SIRT3TRPV1ALDH1A1 | |
| SCHEMBL13719121 | 0.82 | MEN1 (0.67) | TRPV1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7893547 | 0.82 | MEN1 (0.67) | ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107652200-B | A method of N- aryl Zhong Fang amide is synthesized using aryl hydrazine | 陕西科技大学 | 2019-06-14 | — | — | CN | disclosed |
| CN-107652200-A | A kind of method that N aryl Zhong Fang acid amides is synthesized using aryl hydrazine | 陕西科技大学 | 2018-02-02 | — | — | CN | disclosed |