Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200510 | 0.96 | SIRT2 (0.57) | ALDH1A1SIRT2SIRT1SIRT3TRPV1 | |
| SCHEMBL17683761 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SIRT2SIRT1SIRT3TRPV1 | |
| SCHEMBL8462054 | 0.87 | NR1H4 (0.59) | ALDH1A1NR1H4HPSESMN1; SMN2MAPT | |
| SCHEMBL12314962 | 0.86 | KCNK9 (0.69) | ALDH1A1SIRT1NR1H4SMN1; SMN2MAPT | |
| SCHEMBL13779847 | 0.86 | TRPV1 (0.66) | ALDH1A1TRPV1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9979193 | 0.86 | ALDH1A1 (0.62) | ALDH1A1NR1H4SMN1; SMN2MAPTKMT2A | |
| SCHEMBL21449753 | 0.85 | KMT2A (0.70) | ALDH1A1NR1H4SMN1; SMN2MAPTKMT2A | |
| SCHEMBL28197185 | 0.84 | PLAU (0.60) | TRPV1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL12597164 | 0.84 | KMT2A (0.62) | NR1H4HPSEMAPTKMT2AMEN1 | |
| SCHEMBL7295812 | 0.84 | NR1H4 (0.76) | ALDH1A1SIRT2SIRT1SIRT3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | ALDH1A1 3287/4885SIRT2 4128/4885SIRT1 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.