Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.69 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | CFD | P00746 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964495 | 0.90 | LOXL2 (0.62) | KCNK3KCNK9KMT2ASIRT1RAB9A | |
| Hydrochloric Acid SCHEMBL19953267 | 0.89 | LOXL2 (0.62) | KCNK3KCNK9KMT2ASIRT1RAB9A | |
| SCHEMBL28956237 | 0.88 | KMT2A (0.57) | KCNK3KCNK9KMT2AMEN1HPSE | |
| SCHEMBL1229626 | 0.86 | MEN1 (0.71) | KCNK3KCNK9KMT2ASIRT1RAB9A | |
| SCHEMBL22542978 | 0.85 | KCNK3 (0.71) | KCNK3KCNK9KMT2ASIRT1RAB9A | |
| SCHEMBL8902663 | 0.85 | KCNK3 (0.71) | KCNK3KCNK9KMT2ASIRT1RAB9A | |
| SCHEMBL20473774 | 0.85 | KCNK3 (0.71) | KCNK3KCNK9KMT2ASIRT1RAB9A | |
| SCHEMBL28200510 | 0.85 | SIRT2 (0.57) | SIRT1RAB9ANPC1HPSE | |
| SCHEMBL13026980 | 0.85 | KCNK3 (0.72) | KCNK3KCNK9KMT2ARAB9ANPC1 | |
| SCHEMBL1857575 | 0.85 | PTPN1 (0.65) | KCNK3KCNK9KMT2ASIRT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | claimed |
| CN-105669491-B | A kind of acylation method of amine | 苏州大学 | 2017-10-13 | — | — | CN | disclosed |
| CN-105669491-A | Acidylation method of amine | 苏州大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-100335468-C | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2007-09-05 | — | — | CN | disclosed |
| CN-1712398-A | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2005-12-28 | — | — | CN | disclosed |
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |
| CN-1155278-A | Arylthio compounds as antibacteral and antiviral agents | WARNER LAMBERT CO (US) | 1997-07-23 | — | — | CN | disclosed |