Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763627 | 0.79 | AR (0.50) | AR | |
| SCHEMBL18552713 | 0.78 | AR (0.44) | ARHTR2AHTR2CHTR2B | |
| SCHEMBL28200627 | 0.76 | CTRC (0.38) | ALDH1A1KDM4EHTR2ACTRC | |
| SCHEMBL6639638 | 0.76 | ALDH1A1 (0.39) | ARALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL28566867 | 0.76 | AR (0.38) | ARALDH1A1KDM4ETRPV4CTRC | |
| SCHEMBL17604488 | 0.75 | KDM4E (0.42) | ARALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL28201223 | 0.75 | AR (0.41) | ARALDH1A1KDM4EUSP2HTR2A | |
| SCHEMBL12797849 | 0.74 | POLB (0.41) | ALDH1A1MAPTPOLBHTTCTRC | |
| SCHEMBL18704482 | 0.74 | AR (0.41) | ARALDH1A1KDM4EUSP2MAPT | |
| SCHEMBL9366157 | 0.74 | CTRC (0.38) | HTR2AHTR2CPOLBHTTCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105339355-B | Novel CYP17 inhibitor/antiandrogen | 奥赖恩公司 | 2018-02-27 | — | — | CN | claimed |
| CN-105339355-B | Novel CYP17 inhibitor/antiandrogen | 奥赖恩公司 | 2018-02-27 | — | — | CN | disclosed |