SCHEMBL28200700

SCHEMBL28200700

NNC(=O)C(=O)Oc1cccc(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.42
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
BCHE P06276 1/20 0.39
KMT2A Q03164 2/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
TRPA1 O75762 1/20 0.35
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PARP10 Q53GL7 1/20 0.34
SLC2A1 P11166 1/20 0.34
SLC2A4 P14672 1/20 0.34
CTSB P07858 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28200073 0.81 KMT2A (0.43) ALDH1A1GAACES2CES1BCHE
SCHEMBL28692786 0.77 KMT2A (0.45) ALDH1A1GAACES2CES1BCHE
SCHEMBL15836535 0.76 KMT2A (0.44) ALDH1A1GAACES2CES1BCHE
SCHEMBL19358651 0.76 CES2 (0.41) ALDH1A1CES2CES1BCHEKMT2A
SCHEMBL15763907 0.75 CES2 (0.44) ALDH1A1GAACES2CES1BCHE
SCHEMBL6966438 0.74 CES2 (0.47) ALDH1A1CES2CES1BCHEKMT2A
SCHEMBL28200122 0.73 KMT2A (0.40) ALDH1A1GAAKMT2AMAPTNPC1
SCHEMBL31200468 0.73 MAPK1 (0.49) ALDH1A1GAACES2CES1BCHE
SCHEMBL1700833 0.73 MAPK1 (0.49) ALDH1A1GAACES2CES1BCHE
SCHEMBL27555847 0.72 CES2 (0.41) ALDH1A1GAACES2CES1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed