Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987193 | 0.82 | CES2 (0.48) | KMT2AALDH1A1CES2CES1SLC2A1 | |
| SCHEMBL28200700 | 0.81 | ALDH1A1 (0.42) | KMT2AALDH1A1GAACES2CES1 | |
| SCHEMBL6476583 | 0.75 | KMT2A (0.46) | KMT2ACES2CES1SLC2A1SLC2A4 | |
| SCHEMBL28378506 | 0.74 | GAA (0.39) | ALDH1A1GAAMAPTL3MBTL1NPSR1 | |
| SCHEMBL28200699 | 0.74 | ESR1 (0.45) | KMT2AALDH1A1CES2CES1NPC1 | |
| SCHEMBL18668623 | 0.73 | CES2 (0.48) | KMT2AALDH1A1CES2CES1SLC2A1 | |
| SCHEMBL18697360 | 0.73 | CES2 (0.48) | KMT2AALDH1A1CES2CES1SLC2A1 | |
| SCHEMBL15763944 | 0.72 | KMT2A (0.47) | KMT2AALDH1A1CES2CES1MAPT | |
| SCHEMBL515879 | 0.72 | KMT2A (0.41) | KMT2AALDH1A1GAACES2CES1 | |
| SCHEMBL9576776 | 0.71 | TDP1 (0.42) | KMT2AALDH1A1GAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |