Hydrazine

Hydrazine

SCHEMBL28200768

NN.O=[N+]([O-])c1ccc(OS(=O)(=O)O)cc1

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.68
CA2 P00918 8/20 0.68
CA9 Q16790 6/20 0.68
CA12 O43570 5/20 0.55
HTT P42858 1/20 0.53
ALDH1A1 P00352 2/20 0.52
HSP90AA1 P07900 1/20 0.52
CA7 P43166 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA13 Q8N1Q1 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
F2 P00734 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866411 0.96 CA1 (0.67) CA1CA2CA9CA12HTT
Sulfuric Acid SCHEMBL3198737 0.94 CA1 (0.65) CA1CA2CA9CA12HTT
SCHEMBL3519559 0.81 CA2 (1.00) CA1CA2CA9CA12HTT
SCHEMBL866410 0.80 CA1 (0.71) CA1CA2CA9CA12HTT
Hydrazine SCHEMBL28200152 0.80 GPR17 (0.53) CA2HTTCA5AKMT2AGAA
SCHEMBL554006 0.77 CA1 (0.62) CA1CA2CA9CA12HTT
SCHEMBL28361918 0.77 CA1 (0.62) CA1CA2CA9CA12HTT
Sulfuric Acid SCHEMBL28654341 0.77 CA1 (0.62) CA1CA2CA9CA12ALDH1A1
SCHEMBL22832592 0.77 HTR2A (0.66) CA1CA2CA9CA12HTT
SCHEMBL11704991 0.77 CA1 (0.67) CA1CA2CA9CA12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed