Hydrazine

Hydrazine

SCHEMBL28200152

NN.O=[N+]([O-])c1cccc(OS(=O)(=O)O)c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 15/20 0.53
P2RY2 P41231 6/20 0.52
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
GAA P10253 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9000083 0.97 GPR17 (0.55) GPR17P2RY2LMNATSHRGAA
SCHEMBL9005003 0.97 GPR17 (0.55) GPR17P2RY2LMNATSHRGAA
Nitrobenzene SCHEMBL11212894 0.84 ALDH1A1 (0.57) GPR17P2RY2LMNACA2CA5A
SCHEMBL9451297 0.83 CA2 (0.64) GPR17P2RY2LMNATSHRCA2
SCHEMBL7123260 0.83 TSHR (0.57) GPR17P2RY2LMNATSHRCA2
SCHEMBL7145541 0.80 TSHR (0.53) GPR17P2RY2LMNATSHRCA2
SCHEMBL22462541 0.80 TSHR (0.53) GPR17P2RY2LMNATSHRCA2
SCHEMBL17675159 0.80 TSHR (0.53) GPR17P2RY2LMNATSHRCA2
SCHEMBL8690576 0.80 TSHR (0.53) GPR17P2RY2LMNATSHRCA2
Hydrazine SCHEMBL28200768 0.80 CA1 (0.68) LMNACA2CA5AGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663161-A A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed