Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.67 |
| ▸ | CA2 | P00918 | 8/20 | 0.67 |
| ▸ | CA9 | Q16790 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA3 | P07451 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113460 | 0.85 | CA1 (0.62) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL866410 | 0.83 | CA1 (0.71) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL14596865 | 0.83 | CA1 (0.61) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL28498472 | 0.82 | CA1 (0.65) | CA1CA2CA9HTTALDH1A1 | |
| Potassium Ion SCHEMBL1902294 | 0.80 | CA1 (0.67) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL4826239 | 0.80 | CA1 (0.67) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL866411 | 0.80 | CA1 (0.67) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL31634023 | 0.80 | CA1 (0.67) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL11704991 | 0.80 | CA1 (0.67) | CA1CA2CA9HTTALDH1A1 | |
| SCHEMBL17318171 | 0.80 | CA1 (0.67) | CA1CA2CA9HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440452-A | A kind of key intermediate 1- of almotriptan（4- amino-benzyl sulfonyls）The preparation method of pyrrolidines | 嘉兴市第二医院 | 2018-08-24 | — | — | CN | claimed |
| US-20240158424-A1 | METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-05-16 | — | — | US | disclosed |
| EP-4361162-A2 | METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE | Takasago International Corporation (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-115803024-A | Composition comprising arylamide derivatives | 中外制药株式会社 | 2023-03-14 | — | — | CN | disclosed |
| CN-114929669-A | Arylamide derivatives having antitumor activity | 中外制药株式会社 | 2022-08-19 | — | — | CN | disclosed |
| CN-110950781-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2020-04-03 | — | — | CN | disclosed |
| CN-108440452-A | A kind of key intermediate 1- of almotriptan（4- amino-benzyl sulfonyls）The preparation method of pyrrolidines | 嘉兴市第二医院 | 2018-08-24 | — | — | CN | disclosed |
| CN-108440452-A | A kind of key intermediate 1- of almotriptan（4- amino-benzyl sulfonyls）The preparation method of pyrrolidines | 嘉兴市第二医院 | 2018-08-24 | — | — | CN | disclosed |
| US-10023530-B2 | Diamine, polyamic acid, and polyimide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20160264520-A1 | NOVEL DIAMINE, POLYAMIC ACID, AND POLYIMIDE | NISSAN CHEMICAL INDUSTRIES. LTD. (JP) | 2016-09-15 | — | — | US | disclosed |
| WO-2016055947-A1 | ALKYNE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-04-14 | — | — | WO | disclosed |
| WO-2013054351-A1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2013-04-18 | — | — | WO | disclosed |
| WO-2013054351-A1 | HETEROCYCLIC COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2013-04-18 | — | — | WO | disclosed |
| WO-1998039312-A1 | STABLE ARENEDIAZONIUM SALTS, A PROCESS FOR THE PREPARATION THEREOF AND THE USES THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158424-A1 | METHOD FOR PRODUCING DIPHOSPHINE MONOXIDE | TDO2, SCO2, DUOX1 | CA1 851/4885CA2 388/4885CA9 490/4885 |
| US-10023530-B2 | Diamine, polyamic acid, and polyimide | H1-2, H1-4, H1-0 | CA1 383/4885CA2 2174/4885CA9 2321/4885 |
| US-20160264520-A1 | NOVEL DIAMINE, POLYAMIC ACID, AND POLYIMIDE | H1-4, H1-2, H1-5 | CA1 306/4885CA2 2161/4885CA9 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.