Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719081 | 0.87 | TSHR (0.51) | HCAR2TSHRLPAR3LPAR1LPAR2 | |
| SCHEMBL1971252 | 0.85 | GLO1 (0.42) | TSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29066906 | 0.83 | THRB (0.47) | TSHRPOLBALDH1A1THRB | |
| SCHEMBL28578410 | 0.82 | LMNA (0.36) | TSHRPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5059056 | 0.78 | HCAR2 (0.37) | HCAR2TSHRPOLBLPAR3LPAR1 | |
| SCHEMBL27823717 | 0.78 | LPAR3 (0.33) | LPAR3LPAR1LPAR2 | |
| SCHEMBL28661305 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL6138156 | 0.77 | HCAR2 (0.39) | HCAR2TSHRPOLBALDH1A1GAA | |
| SCHEMBL11646015 | 0.77 | HCAR2 (0.39) | HCAR2TSHRPOLBALDH1A1GAA | |
| SCHEMBL28806663 | 0.77 | HCAR2 (0.44) | HCAR2TSHRPOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105713150-B | A kind of preparation method and applications of the polycarboxylate water-reducer of resistance to sulfate | 江苏苏博特新材料股份有限公司 | 2018-06-26 | — | — | CN | claimed |
| CN-107652405-A | A kind of polycarboxylate water-reducer of acid amides/imide structure and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2018-02-02 | — | — | CN | claimed |
| CN-105713150-B | A kind of preparation method and applications of the polycarboxylate water-reducer of resistance to sulfate | 江苏苏博特新材料股份有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-106008784-B | A kind of concrete thinner and preparation method thereof | 中建商品混凝土眉山新材料有限公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-107652405-A | A kind of polycarboxylate water-reducer of acid amides/imide structure and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2018-02-02 | — | — | CN | disclosed |