SCHEMBL28201243

SCHEMBL28201243

CCOP(=O)(OCC)OC(N)CC

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LAP3 P28838 1/20 0.34
PPARD Q03181 2/20 0.32
CYP3A4 P08684 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246018 0.85 LAP3 (0.40) TSHRLAP3CYP3A4L3MBTL1
SCHEMBL30956369 0.81 TSHR (0.57) TSHRTP53TDP1LAP3PPARD
SCHEMBL29204762 0.79 TSHR (0.44) TSHRTP53TDP1LAP3PPARD
SCHEMBL28200676 0.79 LAP3 (0.36) TSHRLAP3
SCHEMBL6014553 0.79 TSHR (0.55) TSHRTP53TDP1PPARDMEN1
SCHEMBL5908843 0.74 TSHR (0.55) TSHRTP53TDP1PPARDCYP3A4
SCHEMBL9749945 0.74 TSHR (0.55) TSHRTP53TDP1PPARDL3MBTL1
Triethyl Phosphate SCHEMBL29254609 0.74 TSHR (0.93) TSHRTP53TDP1PPARDCYP3A4
SCHEMBL9655177 0.73 TSHR (0.60) TSHRTP53TDP1PPARDCYP3A4
SCHEMBL86164 0.73 TSHR (0.60) TSHRTP53TDP1PPARDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372747-B Intrinsic flame-retardant transparent organic silicon fireproof coating and preparation method thereof 北京化工大学 2022-04-26 CN claimed
CN-109517470-B Water-based ultrathin fireproof coating and preparation method thereof 中建西部建设股份有限公司 2021-07-02 CN claimed
CN-113372747-B Intrinsic flame-retardant transparent organic silicon fireproof coating and preparation method thereof 北京化工大学 2022-04-26 CN disclosed
CN-113372747-A Intrinsic flame-retardant transparent organic silicon fireproof coating and preparation method thereof 北京化工大学 2021-09-10 CN disclosed
CN-109517470-B Water-based ultrathin fireproof coating and preparation method thereof 中建西部建设股份有限公司 2021-07-02 CN disclosed
CN-107722166-A A kind of phosphorus nitrogen is cooperateed with from flame-proof acrylic emulsion and preparation method thereof 陈晨特 2018-02-23 CN disclosed