Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956369 | 0.83 | TSHR (0.57) | TSHRTDP1TP53PPARDMEN1 | |
| SCHEMBL11395405 | 0.81 | TSHR (0.40) | TSHRTP53METAP1 | |
| SCHEMBL86164 | 0.80 | TSHR (0.60) | TSHRTDP1TP53PPARDMEN1 | |
| SCHEMBL28201243 | 0.79 | TSHR (0.52) | TSHRTDP1TP53PPARDMEN1 | |
| SCHEMBL1986552 | 0.79 | CTSA (0.36) | METAP1 | |
| SCHEMBL11153181 | 0.77 | TSHR (0.58) | TSHRTDP1TP53METAP1PPARD | |
| SCHEMBL8922103 | 0.76 | TSHR (0.55) | TSHRTDP1TP53PPARDMEN1 | |
| SCHEMBL5908843 | 0.76 | TSHR (0.55) | TSHRTDP1TP53PPARDMEN1 | |
| SCHEMBL6895576 | 0.76 | TSHR (0.55) | TSHRTDP1TP53PPARDMEN1 | |
| SCHEMBL6896826 | 0.76 | TSHR (0.55) | TSHRTDP1TP53PPARDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109517470-B | Water-based ultrathin fireproof coating and preparation method thereof | 中建西部建设股份有限公司 | 2021-07-02 | — | — | CN | claimed |
| CN-104119381-B | A kind of preparation method of fotemustine | SINOPHARM YIXIN PHARMACEUTICAL CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-104119381-A | Preparation method of fotemustine | SINOPHARM A THINK PHARMACEUTICAL CO LTD | 2014-10-29 | — | — | CN | claimed |
| EP-0914390-B1 | INTUMESCENT COMPOSITION AND METHOD | GEORGIA PACIFIC RESINS (US) | 2000-09-20 | — | — | EP | claimed |
| CN-109517470-B | Water-based ultrathin fireproof coating and preparation method thereof | 中建西部建设股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-106146367-A | Allyl sulfenyl amino 1,4-benzoquinone compounds, its preparation and application | 北京大学 | 2016-11-23 | — | — | CN | disclosed |
| CN-104119381-B | A kind of preparation method of fotemustine | SINOPHARM YIXIN PHARMACEUTICAL CO., LTD. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-104119381-B | A kind of preparation method of fotemustine | SINOPHARM YIXIN PHARMACEUTICAL CO., LTD. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-104119381-A | Preparation method of fotemustine | SINOPHARM A THINK PHARMACEUTICAL CO LTD | 2014-10-29 | — | — | CN | disclosed |
| US-7078406-B2 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-6815445-B2 | FOR USE AS FLUORESCENCE DYES AND PROBES | Life Technologies Corporation | 2004-11-09 | — | — | US | disclosed |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | TSHR 4569/4885TDP1 554/4885TP53 3505/4885 |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | DHFR, FPR1, CYP1A1 | TSHR 4569/4885TDP1 554/4885TP53 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.