Methyl Alcohol

Methyl Alcohol

SCHEMBL28201372

CNc1ccc(C(=O)c2ccccc2)cc1[N+](=O)[O-].CO

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.76
HCAR3 P49019 7/20 0.71
VCAM1 P19320 1/20 0.61
MAPK1 P28482 4/20 0.57
HTT P42858 2/20 0.52
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
NPC1 O15118 2/20 0.50
GLA P06280 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
RECQL P46063 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11269607 0.99 CDC25B (0.78) CDC25BHCAR3VCAM1MAPK1HTT
SCHEMBL7376176 0.86 CDC25B (1.00) CDC25BHCAR3ALDH1A1MAPTGLA
Methyl Alcohol SCHEMBL28201843 0.85 HCAR3 (0.73) CDC25BHCAR3VCAM1MAPK1HTT
SCHEMBL11150919 0.84 HCAR3 (0.63) CDC25BHCAR3VCAM1MAPK1HTT
SCHEMBL9630291 0.84 MAPK1 (0.62) CDC25BHCAR3VCAM1MAPK1HTT
SCHEMBL321911 0.83 HCAR3 (1.00) CDC25BHCAR3
SCHEMBL4281287 0.83 HCAR3 (0.79) CDC25BHCAR3VCAM1MAPK1ALDH1A1
Hydrochloric Acid SCHEMBL321637 0.82 HCAR3 (0.97) CDC25BHCAR3
SCHEMBL973813 0.80 HCAR3 (0.77) CDC25BHCAR3MAPK1HTTALDH1A1
Methyl Alcohol SCHEMBL28201441 0.80 HCAR3 (0.76) CDC25BHCAR3VCAM1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107635989-A Benzimidizole derivatives as bromine domain inhibitor 葛兰素史克知识产权开发有限公司 2018-01-26 CN disclosed