Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043949 | 0.87 | HCAR3 (1.00) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| Methyl Alcohol SCHEMBL28201843 | 0.84 | HCAR3 (0.73) | HCAR3MAPTALDH1A1KMT2APKM | |
| SCHEMBL2252228 | 0.84 | MAPT (0.82) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| Methyl Alcohol SCHEMBL28201371 | 0.84 | ALDH1A1 (0.59) | HCAR3MAPTALDH1A1RAB9ABCL2 | |
| SCHEMBL11238552 | 0.83 | HCAR3 (0.77) | HCAR3MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL2552519 | 0.83 | HCAR3 (0.79) | HCAR3MAPTALDH1A1RAB9APTGER4 | |
| SCHEMBL11544539 | 0.83 | KMT2A (0.58) | HCAR3MAPTALDH1A1RAB9ABCL2 | |
| SCHEMBL28201836 | 0.82 | ALDH1A1 (0.60) | HCAR3MAPTALDH1A1RAB9ABCL2 | |
| Methyl Alcohol SCHEMBL28856375 | 0.82 | HCAR3 (0.51) | HCAR3MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL1964842 | 0.80 | MAPT (1.00) | HCAR3MAPTALDH1A1RAB9APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635989-A | Benzimidizole derivatives as bromine domain inhibitor | 葛兰素史克知识产权开发有限公司 | 2018-01-26 | — | — | CN | disclosed |