Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044176 | 0.87 | HCAR3 (1.00) | HCAR3NPC1SMN1; SMN2MAPTPKM | |
| Methyl Alcohol SCHEMBL28201843 | 0.86 | HCAR3 (0.73) | HCAR3MAPTPKMALDH1A1POLB | |
| SCHEMBL11544539 | 0.85 | KMT2A (0.58) | HCAR3NPC1MAPTPKMALDH1A1 | |
| SCHEMBL11267808 | 0.85 | HCAR3 (0.81) | HCAR3NPC1SMN1; SMN2MAPTRXFP1 | |
| SCHEMBL28201836 | 0.84 | ALDH1A1 (0.60) | HCAR3NPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL6044024 | 0.84 | HCAR3 (1.00) | HCAR3NPC1SMN1; SMN2MAPTPKM | |
| Methyl Alcohol SCHEMBL28201371 | 0.83 | ALDH1A1 (0.59) | HCAR3NPC1SMN1; SMN2MAPTPKM | |
| Methyl Alcohol SCHEMBL28201441 | 0.83 | HCAR3 (0.76) | HCAR3NPC1MAPTPKMALDH1A1 | |
| SCHEMBL6044600 | 0.82 | HCAR3 (0.97) | HCAR3NPC1MAPTPKMALDH1A1 | |
| SCHEMBL11208444 | 0.82 | HCAR3 (0.97) | HCAR3NPC1MAPTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310537-A | ANTHELMINTICS AND FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4060636-A | Acetyl- and carbalkoxythioureidobenzophenones as anthelmintic agents | ROHM AND HAAS COMPANY (US) | 1977-11-29 | — | — | US | disclosed |