Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17393728 | 0.76 | TSHR (0.41) | TSHRHIF1ACYP2D6CYP2C19THRB | |
| SCHEMBL466312 | 0.72 | — | — | |
| SCHEMBL15247345 | 0.72 | THRB (0.36) | TSHRHIF1ACYP2D6CYP2C19THRB | |
| SCHEMBL13865876 | 0.72 | GAA (0.44) | TSHRHIF1ACYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL15463204 | 0.71 | THRB (0.35) | TSHRHIF1ACYP2D6CYP2C19THRB | |
| SCHEMBL1148669 | 0.71 | TSHR (0.46) | TSHRHIF1ATHRBHPGDALDH1A1 | |
| SCHEMBL7189835 | 0.71 | TSHR (0.46) | TSHRHIF1ATHRBHPGDALDH1A1 | |
| SCHEMBL7192242 | 0.71 | TSHR (0.46) | TSHRHIF1ATHRBHPGDALDH1A1 | |
| SCHEMBL7192231 | 0.71 | TSHR (0.46) | TSHRHIF1ATHRBHPGDALDH1A1 | |
| SCHEMBL588612 | 0.70 | ALDH1A1 (0.54) | TSHRHIF1ACYP2D6ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107615171-A | Manufacture method, circuit layout, input unit and the display device of circuit layout | 富士胶片株式会社 | 2018-01-19 | — | — | CN | disclosed |