Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316709 | 0.86 | APP (0.58) | APPMAPTPOLBNPC1KDM4E | |
| SCHEMBL4310633 | 0.86 | LTA4H (0.56) | APPALOX5MAPTL3MBTL1POLB | |
| SCHEMBL28201923 | 0.86 | MAOB (0.48) | MAPTL3MBTL1ACHENPC1KDM4E | |
| SCHEMBL12973226 | 0.82 | APP (0.83) | APPALOX5MAPTACHENPC1 | |
| SCHEMBL27968344 | 0.81 | TP53 (0.51) | APPMAPTACHENPC1KDM4E | |
| SCHEMBL14030856 | 0.78 | ACHE (0.62) | ALOX5MAPTMAPK1L3MBTL1ACHE | |
| SCHEMBL19087101 | 0.78 | ACHE (0.62) | ALOX5MAPTMAPK1L3MBTL1ACHE | |
| SCHEMBL28201931 | 0.78 | HTT (0.38) | ALOX5MAPK1NPC1KDM4EALDH1A1 | |
| SCHEMBL10331951 | 0.77 | APP (0.68) | APPMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL28992994 | 0.76 | APP (0.61) | APPMAPTNPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |