Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28176950 | 0.90 | NNMT (0.50) | NNMTHDAC1HDAC6SMN1; SMN2GABRA1 | |
| SCHEMBL351856 | 0.89 | NNMT (0.61) | NNMTHDAC1HDAC6SMN1; SMN2GABRA1 | |
| SCHEMBL30231615 | 0.89 | NNMT (0.61) | NNMTHDAC1HDAC6SMN1; SMN2GABRA1 | |
| SCHEMBL30303086 | 0.77 | HDAC1 (0.55) | NNMTHDAC1HDAC6SMN1; SMN2GABRA1 | |
| SCHEMBL8018191 | 0.74 | HDAC1 (0.60) | HDAC1HDAC6SMN1; SMN2GRM5KDM4E | |
| SCHEMBL1857619 | 0.73 | HDAC1 (0.47) | HDAC1HDAC6SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL4400941 | 0.73 | HDAC1 (0.64) | HDAC1HDAC6SMN1; SMN2KDM4ELMNA | |
| SCHEMBL1993840 | 0.73 | GRM5 (0.58) | NNMTSMN1; SMN2GRM5KDM4EL3MBTL1 | |
| SCHEMBL30074957 | 0.72 | HDAC1 (0.50) | HDAC1HDAC6SMN1; SMN2GABRA1KDM4E | |
| SCHEMBL1856776 | 0.72 | HDAC1 (0.50) | HDAC1HDAC6SMN1; SMN2GABRA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812762-B | Substituted cyclic pyrimidin and triazine and their purposes | 拜耳药业股份公司 | 2018-01-16 | — | — | CN | disclosed |