SCHEMBL28201697

SCHEMBL28201697

CCCCc1cnc(N)nc1N

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.56
DHFR P00374 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1554275 0.94 PKM (0.55) PKMDHFR
SCHEMBL29352921 0.94 PKM (0.55) PKMDHFR
SCHEMBL30872658 0.93 PKM (0.54) PKMDHFR
SCHEMBL16701417 0.93 PKM (0.54) PKMDHFR
SCHEMBL16701413 0.93 PKM (0.54) PKMDHFR
SCHEMBL9499492 0.93 PKM (0.54) PKMDHFR
Benzene SCHEMBL27894272 0.91 PKM (0.52) PKMDHFR
SCHEMBL2450159 0.88 DHFR (0.59) PKMDHFR
SCHEMBL30715140 0.88 DHFR (0.59) PKMDHFR
Hydrochloric Acid SCHEMBL28530443 0.86 DHFR (0.57) PKMDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107739371-A A kind of Tetrahydrocarbazolesand small molecular organic compounds and its purposes in antibacterials are prepared and preparation method thereof 华东师范大学 2018-02-27 CN disclosed