SCHEMBL16701413

SCHEMBL16701413

CCCCCCCc1cnc(N)nc1N

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.54
DHFR P00374 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16701417 1.00 PKM (0.54) PKMDHFR
SCHEMBL9499492 1.00 PKM (0.54) PKMDHFR
SCHEMBL30872658 1.00 PKM (0.54) PKMDHFR
SCHEMBL29352921 0.98 PKM (0.55) PKMDHFR
SCHEMBL1554275 0.98 PKM (0.55) PKMDHFR
Benzene SCHEMBL27894272 0.95 PKM (0.52) PKMDHFR
SCHEMBL28201697 0.93 PKM (0.56) PKMDHFR
SCHEMBL3779797 0.85 PKM (0.48) PKMDHFR
SCHEMBL2450159 0.85 DHFR (0.59) PKMDHFR
SCHEMBL30715140 0.85 DHFR (0.59) PKMDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015069752-A9 ACETYLCHOLINE BINDING PROTEIN LIGANDS, COOPERATIVE NACHR MODULATORS AND METHODS FOR MAKING AND USING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-07-09 WO disclosed
WO-2015069752-A1 ACETYLCHOLINE BINDING PROTEIN LIGANDS, COOPERATIVE NACHR MODULATORS AND METHODS FOR MAKING AND USING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-05-14 WO disclosed