Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376861 | 0.77 | L3MBTL1 (0.38) | CYP11B1CYP11B2LMNATSHRKCNN4 | |
| SCHEMBL5744574 | 0.77 | LMNA (0.38) | CYP11B1CYP11B2LMNATSHRKCNN4 | |
| SCHEMBL8290753 | 0.77 | L3MBTL1 (0.38) | CYP11B1CYP11B2LMNATSHRKCNN4 | |
| SCHEMBL18803166 | 0.75 | LMNA (0.34) | CYP11B1CYP11B2LMNAKCNA3L3MBTL1 | |
| SCHEMBL30537611 | 0.71 | CHRM3 (0.35) | LMNAALDH1A1CHRM3CHRM2CHRM1 | |
| Lithium Ion SCHEMBL29888438 | 0.71 | CHRM3 (0.35) | LMNAALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL23274047 | 0.71 | CHRM2 (0.38) | ALDH1A1CHRM3CHRM2CHRM1KMT2A | |
| SCHEMBL23415503 | 0.71 | LMNA (0.34) | LMNATSHRALDH1A1KCNA3L3MBTL1 | |
| SCHEMBL991996 | 0.71 | CHRM2 (0.38) | ALDH1A1CHRM3CHRM2CHRM1KMT2A | |
| SCHEMBL23415499 | 0.71 | CYP11B1 (0.32) | CYP11B1CYP11B2LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641114-A | Compound and its application as isocitric dehydrogenase inhibitor | 南京圣和药业股份有限公司 | 2018-01-30 | — | — | CN | disclosed |