Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376861 | 1.00 | L3MBTL1 (0.38) | L3MBTL1CYP2B6SIGMAR1ATMCYP11B1 | |
| SCHEMBL5743664 | 0.78 | MAPT (0.36) | L3MBTL1CYP2B6ATMCHRM3LMNA | |
| SCHEMBL5744574 | 0.77 | LMNA (0.38) | L3MBTL1CYP2B6ATMCYP11B1CYP11B2 | |
| SCHEMBL30214804 | 0.75 | L3MBTL1 (0.39) | L3MBTL1CHRM3LMNACHRM2CHRM1 | |
| SCHEMBL6178086 | 0.74 | ALDH1A1 (0.38) | SIGMAR1CHRM3LMNACHRM2CHRM1 | |
| SCHEMBL6178088 | 0.74 | ALDH1A1 (0.38) | SIGMAR1CHRM3LMNACHRM2CHRM1 | |
| SCHEMBL19801492 | 0.74 | ATM (0.38) | L3MBTL1CYP2B6ATMMAPK1CHRM3 | |
| SCHEMBL28748077 | 0.73 | CHRM3 (0.40) | L3MBTL1CYP2B6ATMCHRM3LMNA | |
| SCHEMBL5743622 | 0.71 | CYP2D6 (0.42) | L3MBTL1ATMKCNN4MAPK1CHRM3 | |
| SCHEMBL23415503 | 0.71 | LMNA (0.34) | L3MBTL1SIGMAR1ATMMAPK1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | L3MBTL1 2796/4885CYP2B6 605/4885SIGMAR1 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.