SCHEMBL28201997

SCHEMBL28201997

C=C(C(=O)O)C1CCCNC1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
TSHR P16473 2/20 0.64
SLC6A11 P48066 2/20 0.64
SLC6A13 Q9NSD5 2/20 0.64
LMNA P02545 1/20 0.64
KDM4E B2RXH2 1/20 0.57
MAPT P10636 1/20 0.57
KMT2A Q03164 1/20 0.57
ATM Q13315 1/20 0.57
CYP2D6 P10635 1/20 0.57
NOS2 P35228 1/20 0.47
CPN1 P15169 2/20 0.39
CPB2 Q96IY4 2/20 0.39
POLB P06746 1/20 0.37
GABRA5 P31644 2/20 0.35
GABRB2 P47870 2/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19816093 0.79 SLC6A1 (0.69) SLC6A1SMN1; SMN2TSHRSLC6A11SLC6A13
Nipecotic Acid SCHEMBL27460458 0.79 SLC6A1 (0.91) SLC6A1SMN1; SMN2TSHRSLC6A11SLC6A13
(S)-Nipecotic Acid SCHEMBL254683 0.79
(R)-Nipecotic Acid SCHEMBL520075 0.79
SCHEMBL12658636 0.79
SCHEMBL8059207 0.79
Nipecotic Acid SCHEMBL85677 0.79
(R)-Nipecotic Acid SCHEMBL29880539 0.79
Nipecotic Acid SCHEMBL456856 0.79 SLC6A1 (1.00) SLC6A1SMN1; SMN2TSHRSLC6A11SLC6A13
(R)-Nipecotic Acid SCHEMBL20562073 0.77 SLC6A1 (0.95) SLC6A1SMN1; SMN2TSHRSLC6A11SLC6A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107759537-A The preparation method of 3 piperidyl acrylate 王明春 2018-03-06 CN claimed
CN-115052639-A Angiogenesis device 信越化学工业株式会社 2022-09-13 CN disclosed
CN-107759537-A The preparation method of 3 piperidyl acrylate 王明春 2018-03-06 CN disclosed