Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 5/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700773 | 0.82 | CASP6 (0.53) | PIK3R1PIK3CAHSD17B10GAACASP6 | |
| SCHEMBL3251579 | 0.81 | PIK3R1 (0.48) | PIK3R1PIK3CAHSD17B10GAACASP6 | |
| SCHEMBL28267735 | 0.79 | POLB (0.41) | PIK3R1PIK3CAHSD17B10GAAUSP2 | |
| SCHEMBL13930938 | 0.79 | RAB9A (0.58) | PIK3R1PIK3CAHSD17B10GAAUSP2 | |
| SCHEMBL4990889 | 0.78 | PIK3R1 (0.51) | PIK3R1PIK3CAHSD17B10GAAUSP2 | |
| SCHEMBL23567450 | 0.77 | PIK3R1 (0.53) | PIK3R1PIK3CAHSD17B10USP2MEN1 | |
| SCHEMBL29550378 | 0.77 | PIK3R1 (0.53) | PIK3R1PIK3CAHSD17B10USP2MEN1 | |
| SCHEMBL30608864 | 0.77 | TAAR1 (0.54) | PIK3R1PIK3CAKDM4EALDH1A1ADORA2A | |
| SCHEMBL21783928 | 0.77 | KDM4E (0.51) | HSD17B10GAAUSP2MEN1KMT2A | |
| SCHEMBL26673561 | 0.77 | TAAR1 (0.54) | PIK3R1PIK3CAKDM4EALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107674070-A | A kind of cyano group imines thiazolidine furoyl amine compound and its preparation method and application | 华南农业大学 | 2018-02-09 | — | — | CN | disclosed |